What is Tadalafila 20 mg used for?
Tadalafil 20 mg is used primarily for the following purposes:
1. Treatment of erectile dysfunction (ED)
Mechanism for action:
-Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE-5). This enzyme is responsible for degrading nitrogen monoxide (no)-cyclic monophosphate dependent guanosin (cGMP) in the smooth vascular muscle of the penis. By inhibiting PDE-5, tadalafil increases cGMP concentration, causing smooth muscle relaxation and increased blood flow to the penis, facilitating erection.
-unlike some other drugs for ED, tadalafil has a long duration of action. A single 20 mg tablet can have an effect for approximately 36 hours, known as the prolonged therapeutic window. This gives patients greater flexibility in terms of planning sexual activity compared to drugs with a shorter duration of action.
2. Treatment of pulmonary arterial hypertension (HTPA)
Mechanism of action at HTPA:
-in HTPA, tadalafil works by relaxing the smooth muscles of the pulmonary arteries. This reduces pulmonary vascular resistance, which in turn decreases pulmonary blood pressure. By improving pulmonary hemodynamics, tadalafil can improve exercise capacity, quality of life and survival in patients with ATP.
It is important to note that tadalafil should be prescribed by a doctor and its use must be accompanied by adequate diagnosis and medical follow-up. In addition, it may have adverse effects, such as headaches, dizziness, back pain, nasal congestion, among others.